Vegetarian diets and risk of hospitalisation or death with diabetes in British adults: results from the EPIC-Oxford study.

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Vegetarian diets and risk of hospitalisation or death with diabetes in British adults: results from the EPIC-Oxford study.

Nutr Diabetes. 2019 02 25;9(1):7

Authors: Papier K, Appleby PN, Fensom GK, Knuppel A, Perez-Cornago A, Schmidt JA, Tong TYN, Key TJ

Abstract
BACKGROUND: The global prevalence of diabetes is high and rapidly increasing. Some previous studies have found that vegetarians might have a lower risk of diabetes than non-vegetarians.
OBJECTIVE: We examined the association between vegetarianism and risk of hospitalisation or death with diabetes in a large, prospective cohort study of British adults.
METHODS: The analysed cohort included participants from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Oxford study who were diabetes free at recruitment (1993-2001), with available dietary intake data at baseline, and linked hospital admissions and death data for diabetes over follow-up (n?=?45,314). Participants were categorised as regular meat eaters (?50?g per day: n?=?15,181); low meat eaters (<50?g of meat per day: n?=?7615); fish eaters (ate no meat but consumed fish: n?=?7092); and vegetarians (ate no meat or fish, including vegans: n?=?15,426). We used multivariable Cox proportional hazards models to assess associations between diet group and risk of diabetes.
RESULTS: Over a mean of 17.6 years of follow-up, 1224 incident cases of diabetes were recorded. Compared with regular meat eaters, the low meat eaters, fish eaters, and vegetarians were less likely to develop diabetes (hazard ratio (HR)?=?0.63, 95% confidence interval (CI) 0.54-0.75; HR?=?0.47, 95% CI 0.38-0.59; and HR?=?0.63, 95% CI 0.54-0.74, respectively). These associations were substantially attenuated after adjusting for body mass index (BMI) (low meat eaters: HR?=?0.78, 95% CI 0.66-0.92; fish eaters: HR?=?0.64, 95% CI 0.51-0.80; and vegetarians: HR?=?0.89, 95% CI 0.76-1.05).
CONCLUSIONS: Low meat and non-meat eaters had a lower risk of diabetes, in part because of a lower BMI.

PMID: 30804320 [PubMed - indexed for MEDLINE]

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